Test Code LAB352 5-Hydroxyindoleacetic Acid (5-HIAA), 24 Hour, Urine
Additional Codes
Mayo Test Code: HIAA
Reporting Name
5-Hydroxyindoleacetic Acid, UUseful For
Biochemical diagnosis and monitoring of intestinal carcinoid syndrome
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory

Specimen Type
UrineNecessary Information
24-hour volume is required.
Specimen Required
Patient Preparation:
1. Some prescription medications could interfere with test results. The ordering provider should decide if any medications should be stopped and when they should be restarted.
2. For 48 hours before patients start their urine collection and during the 24 hours they collect urine:
Limit the following to 1 serving per day:
-Fruits
-Vegetables
-Nuts
-Caffeinated beverages or foods
If clinically feasible, discontinue the following medications at least 48 hours before specimen collection:
-Acetaminophen (Tylenol or generic versions)
-Aspirin
-Antihistamines
-Cough syrups
-Cold and flu medications
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube (T068)
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a 24-hour urine specimen.
2. Add 25 mL of 50% acetic acid as preservative at start of collection. Use 15 mL of 50% acetic acid for children <5 years old.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 56 days |
Frozen | 365 days |
Reject Due To
Hemolysis |
NA |
Lipemia |
NA |
Icterus |
NA |
Other |
NA |
Special Instructions
Reference Values
≤8 mg/24 hours
For SI unit Reference Values, see https://www.mayomedicallaboratories.com/order-tests/si-unit-conversion.html.
Day(s) and Time(s) Performed
Monday through Thursday; 11 a.m.; Friday: 2 p.m.
CPT Code Information
83497
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HIAA | 5-Hydroxyindoleacetic Acid, U | In Process |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
9248 | 5-Hydroxyindoleacetic Acid, U | 1695-6 |
TM35 | Collection Duration | 13362-9 |
VL33 | Urine Volume | 3167-4 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.Forms
If not ordering electronically, complete, print, and send an Oncology Test Request Form (T729) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/oncology-request-form.pdf)