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Test Code LAB835 Methylmalonic Acid (MMA), Quantitative, Serum

Additional Codes

Mayo Test Code: MMAS

Reporting Name

Methylmalonic Acid, QN, S

Useful For

Evaluating children with signs and symptoms of methylmalonic acidemia


Evaluating individuals with signs and symptoms associated with a variety of causes of cobalamin (vitamin B12) deficiency

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type


Specimen Required


Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1.5 mL

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 48 days
  Ambient  48 days
  Frozen  48 days

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross OK



Reference Values

≤0.40 nmol/mL

Day(s) and Time(s) Performed

Monday through Friday; Continuously until noon

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
MMAS Methylmalonic Acid, QN, S 13964-2


Result ID Test Result Name Result LOINC Value
80289 Methylmalonic Acid, QN, S 13964-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

General Request Form (T239) (

Benign Hematology Test Request Form (T755) (