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Test Code LAB3308 Serotonin, 24 Hour, Urine

Additional Codes

Mayo Test Code: SERU

Reporting Name

Serotonin, 24 Hr, U

Useful For

The diagnosis of a small subgroup of carcinoid tumors that produce predominately 5-hydroxytryptophan (5-HTP), but very little serotonin and chromogranin A

 

Follow-up of patients with known or treated carcinoid tumors that produce predominately 5-HTP, but very little serotonin and chromogranin A

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Container/Tube: Plastic, 10-mL urine tube (T068)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect urine for 24-hours.

2. Add 25 mL of 50% acetic acid as preservative at start of collection.

3. Refrigerate specimen during collection.

4. Patients should not eat avocados, bananas, butternuts, cantaloupe, dates, eggplant, grapefruit, hickory nuts, honeydew melon, kiwifruit, melon, nuts, pecans, pineapple, plantains, plums, tomatoes, or walnuts, which are high in serotonin for 48 hours before or during collection.

Additional Information:

1. 24-Hour volume is required.

2. See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen (preferred) 14 days
  Refrigerated  7 days

Reference Values

≤210 mcg/24 hours 

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday, Wednesday, Friday; 10 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84260

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SERU Serotonin, 24 Hr, U 18253-5

 

Result ID Test Result Name Result LOINC Value
26603 Serotonin, 24 Hr, U 18253-5
TM80 Collection Duration 13362-9
VL67 Urine Volume 3167-4

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Urine Preservative Collection Options

Ambient

No

Refrigerated

Preferred

Frozen

Yes

6N HCl

No

50% Acetic Acid

Preferred

Na2CO3

No

Toluene

Yes

6N HNO3

Yes

Boric Acid

No

Thymol

No

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request Form (T729) with the specimen

(http://www.mayomedicallaboratories.com/it-mmfiles/oncology-request-form.pdf)