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Test Code LAB3255 Neuroimmunology Antibody Follow-up, Serum

Additional Codes

Mayo Test Code: PNEFS

Reporting Name

Neuroimmunology Ab Follow-up, S

Useful For

Monitoring patients who have previously tested positive for 1 or more antibodies in the Mayo Neuroimmunology Laboratory within the past 5 years.

 

Requests for the follow-up assay in serum specimens must have previously been positive in a serum evaluation.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 4 mL


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

Test ID

Reporting Name

Reference Value

GANG

AChR Ganglionic Neuronal Ab, S

<0.02

AMPCS

AMPA-R Ab CBA, S

Negative

AMPIS

AMPA-R Ab IF Titer Assay, S

<1:120

AMPHS

Amphiphysin Ab, S

<1:240

ABLOT

Amphiphysin Western Blot, S

Negative

AGN1S

Anti-Glial Nuclear Ab, Type 1

<1:240

ANN1S

Anti-Neuronal Nuclear Ab, Type 1

<1:240

ANN2S

Anti-Neuronal Nuclear Ab, Type 2

<1:240

ANN3S

Anti-Neuronal Nuclear Ab, Type 3

<1:240

CS2CS

CASPR2-IgG CBA, S

Negative

CRMS

CRMP-5-IgG, S

<1:240

GABCS

GABA-B-R Ab CBA, S

Negative

GABIS

GABA-B-R Ab IF Titer Assay, S

<1:120

LG1CS

LGI1-IgG CBA, S

Negative

VGKC

Neuronal (V-G) K+ Channel Ab, S

<0.02

NMDCS

NMDA-R Ab CBA, S

Negative

NMDIS

NMDA-R Ab IF Titer Assay, S

<1:120

NMOTS

NMO/AQP4 FACS Titer, S

<1:5

CCN

N-Type Calcium Channel Ab

<0.03

CCPQ

P/Q-Type Calcium Channel Ab

<0.02

WBN

Paraneoplastic Autoantibody WBlot,S

Negative

PCABP

Purkinje Cell Cytoplasmic Ab Type 1

<1:240

PCAB2

Purkinje Cell Cytoplasmic Ab Type 2

<1:240

PCATR

Purkinje Cell Cytoplasmic Ab Type Tr

<1:240

Day(s) and Time(s) Performed

ANN1S, ANN2S, ANN3S, AGN1S, PCABP, PCAB2, PCATR, AMPHS, CRMS, AMPIS, GABIS, NMDIS: Monday through Friday; 11:30 a.m. and 8 p.m.; Saturday and Sunday 8 a.m.

AMPCS, GABCS, NMDCS. LG1CS, CS2CS: Monday through Friday; 6 a.m.

Paraneoplastic autoantibody Western blot confirmation, CRMP-5-IgG Western blot, Amphiphysin Western blot: Monday, Wednesday, Friday; 8 a.m.

CCPQ, CCN, GANG, VGKC: Monday through Friday 11 a.m. and 6 p.m.; Saturday 6 a.m.; Sunday 6 a.m.

ACh receptor (muscle) modulating antibodies: Monday through Thursday, Saturday; 12 p.m., Saturday; 8 a.m.

CPT Code Information

83519-59-ACh receptor (muscle) modulating antibodies (if appropriate)

83519-59-AChR ganglionic neuronal antibody (if appropriate)

83519-59-N-type calcium channel antibody (if appropriate)

83519-59-P/Q-type calcium channel antibody (if appropriate)

83519-VGKC (if appropriate)

84182-CRMP-5-IgG Western blot (if appropriate)

84182-Paraneoplastic autoantibody Western blot confirmation (if appropriate)

86255-Amphiphysin (if appropriate)

86255-ANNA-1 (if appropriate)

86255-ANNA-2 (if appropriate)

86255-ANNA-3 (if appropriate)

86255-CRMP-5-IgG (if appropriate)

86255-PCA-1 (if appropriate)

86255-PCA-2 (if appropriate)

86255-PCA-Tr (if appropriate)

86255-NMDCS (if appropriate)

86255-AMPCS (if appropriate)

86255-GABCS (if appropriate)

86256-NMDIS (if appropriate)

86256-AMPIS (if appropriate)

86256-GABIS (if appropriate)

86255-LG1CS (if appropriate)

86255-CS2CS (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PNEFS Neuroimmunology Ab Follow-up, S In Process

 

Result ID Test Result Name Result LOINC Value
84300 Neuroimmunology Ab Follow-up, S No LOINC Needed

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ARMO ACh Receptor (Muscle) Modulating Ab No No
GANG AChR Ganglionic Neuronal Ab, S No No
AMPCS AMPA-R Ab CBA, S No No
AMPIS AMPA-R Ab IF Titer Assay, S No No
AMPHS Amphiphysin Ab, S No No
ABLOT Amphiphysin Western Blot, S No No
AGN1S Anti-Glial Nuclear Ab, Type 1 No No
ANN1S Anti-Neuronal Nuclear Ab, Type 1 No No
ANN2S Anti-Neuronal Nuclear Ab, Type 2 No No
ANN3S Anti-Neuronal Nuclear Ab, Type 3 No No
CS2CS CASPR2-IgG CBA, S No No
CRMWS CRMP-5-IgG Western Blot, S No No
CRMS CRMP-5-IgG, S No No
GABCS GABA-B-R Ab CBA, S No No
GABIS GABA-B-R Ab IF Titer Assay, S No No
LG1CS LGI1-IgG CBA, S No No
VGKC Neuronal (V-G) K+ Channel Ab, S No No
NMDCS NMDA-R Ab CBA, S No No
NMDIS NMDA-R Ab IF Titer Assay, S No No
CCN N-Type Calcium Channel Ab No No
CCPQ P/Q-Type Calcium Channel Ab No No
WBN Paraneoplastic Autoantibody WBlot,S No No
PCABP Purkinje Cell Cytoplasmic Ab Type 1 No No
PCAB2 Purkinje Cell Cytoplasmic Ab Type 2 No No
PCATR Purkinje Cell Cytoplasmic Ab Type Tr No No

Method Name

ANN1S, ANN2S, ANN3S, AGN1S, PCABP, PCAB2, PCATR, AMPHS, CRMS, AMPIS, GABIS, NMDIS: Indirect Immunofluorescence (IFA)

AMPCS, GABCS, NMDCS, LG1CS, CS2CS: Cell-Binding Assay (CBA)

WBN, CRMWS, ABLOT: Western Blot

CCPQ, CCN, GANG, VGKC, ARMO: Radioimmunoassay (RIA)

Test Classification

Manually Entered

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/neurology-request-form.pdf)