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Test Code HBVQU Hepatitis B Virus (HBV) DNA Detection and Quantification by Real-Time PCR, Serum

Reporting Name

HBV DNA Detect/Quant, S

Useful For

Confirmation of chronic hepatitis B virus (HBV) infection


Quantification of HBV DNA in serum of patients with chronic HBV infection (previously hepatitis B surface antigen-positive)


Monitoring disease progression in chronic HBV infection and/or response to anti-HBV therapy

Testing Algorithm

The following algorithms are available in Special Instructions:

-HBV Infection-Diagnostic Approach and Management Algorithm

-HBV Infection-Monitoring Before and After Liver Transplantation

Method Name

Real-Time Polymerase Chain Reaction (PCR)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum SST

Specimen Required

Collection Container/Tube: Serum gel

Submission Container/Tube: Polypropylene vial (T465)

Specimen Volume: 1.5 mL

Collection Instructions: 

1. Spin down and separate serum from gel within 6 hours of draw.

2. Freeze specimen immediately, and ship frozen on dry ice.

3. If shipment will be delayed for >24 hours, freeze specimen at -70° C (up to 35 days) until shipment on dry ice.

Specimen Minimum Volume

0.80 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum SST Frozen

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross OK



Reference Values


Day(s) and Time(s) Performed

Monday through Friday; Varies

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
HBVQU HBV DNA Detect/Quant, S In Process


Result ID Test Result Name Result LOINC Value
88634 HBV DNA Detect/Quant, S 42595-9

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

General Request Form (T239) (

Gastroenterology and Hepatology Test Request Form (T728) (