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Test Code FLCP Immunoglobulin Free Light Chains, Serum

Reporting Name

Immunoglobulin Free Light Chains, S

Useful For

Monitoring patients with monoclonal light chain diseases but no M-spike on protein electrophoresis

Profile Information

Test ID Reporting Name Available Separately Always Performed
KFLC Kappa Free Light Chain, S No Yes
LFLC Lambda Free Light Chain, S No Yes
KLR Kappa/Lambda FLC Ratio No Yes

Testing Algorithm

The following algorithms are available in Special Instructions:

-Laboratory Approach to the Diagnosis of Amyloidosis

-Laboratory Screening Tests for Suspected Multiple Myeloma

Method Name

Nephelometry

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  21 days
  Ambient  72 hours

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

KAPPA-FREE LIGHT CHAIN

0.33-1.94 mg/dL

 

LAMBDA-FREE LIGHT CHAIN

0.57-2.63 mg/dL

 

KAPPA/LAMBDA FLC RATIO

0.26-1.65

Day(s) and Time(s) Performed

Monday through Saturday; Continuously until 3 p.m.

CPT Code Information

83883 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLCP Immunoglobulin Free Light Chains, S 57778-3

 

Result ID Test Result Name Result LOINC Value
KFLC Kappa Free Light Chain, S 36916-5
KLR Kappa/Lambda FLC Ratio 48378-4
LFLC Lambda Free Light Chain, S 33944-0

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

General Request Form (T239) (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf)

Hematopathology/Cytogenetics Test Request Form (T726) (http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf)