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Test Code 66801 Verify Now Platelet Function P2Y12

Performing Laboratory

Eisenhower Medical Center

Department

Main Lab - Transfusion Services

Method

Main Lab: Verify Now Platelet Function Assay

Specimen

Whole Blood

Specimen Containers

Two Blue 2 mL white top tubes

Collection Volume

0.1

Specimen Handling

Hand Deliver/No Spin

Procedural Instructions

For both Plavix and Aspirin, low HCT or platelet counts can affect results. If so, a value will not be generated by
the assay system. If Reopro (abciximab) was given within the past two weeks, or Integrilin (eptifibitide) within the past two days, platelet inhibition studies cannot be determined for either assay

Collection Instructions

Hand Deliver/No Spin

Transport Requirements

No Spin / Deliver STAT to Transfusion Services

Interpretative Comments

The following table relates the PRU value reported to

the expected level of platelet inhibition:

PRU THRESHOLD---APPROXIMATE % Inhibition level

  259-----------------10%

  237-----------------20%

  214-----------------30%

  187-----------------40%

  159-----------------50%

  131-----------------60%

  <130--------------->60%

 

Recommended Therapeutic Range: PRU values less than

194 are specific evidence of antiplatelet effect due

to P2Y12 receptor blockade.

 

Analyte

Platelet Function P2Y12